Tagged with “inherited cancer”

Risk for Lynch Syndrome Related Cancers in MSH6 Mutations

People with a mutation in the MSH6 gene, part of the Lynch syndrome, have a greatly increased risk of colorectal, endometrial, and other related cancers. The cancers can occur in old age, with an increasing risk from age 70 to 80.

About 4 in every 1000 colorectal cancers are due to an inherited mutation in the MSH6 gene. It accounts for about 10 to 20 percent of Lynch syndrome mutations.

By the time they are 80 years old, men have eight times the risk of getting colorectal cancer and women have 26 times the risk of endometrial cancer — cancer that begins in the lining of the uterus.

Posted by Kate Murphy on December 23rd, 2009
Posted in: Research & Treatment News | No Comments »
Tags: inherited cancer, Lynch syndrome, MSH6

Search C3

Win Tickets to the US Open Series

Make a donation to the Colorectal Cancer Coalition before Aug 5th for a chance to win tickets to the US Open Series in the following cities: Washington, DC; San Diego, CA; Cincinnati, OH; and New Haven, CT.

Donate and enter!

Good luck!

Sweepstakes ends on Thursday, August 5. Click here for official rules.

Follow C3

Join us on Facebook

Watch us on YouTube

Register to receive our free e-newsletter

Get monthly updates on colorectal cancer treatment options, research news and advocacy opportunities. We promise to not bombard you with email - just enough to keep you informed on how to fight colorectal cancer.